Tie breakers: If two or more teams are still level based on points, goal difference, goals scored and head-to-head results, then the fair play system will be used.
The Three Lions will qualify if they draw against Wales on Tuesday.
Southgate’s side would move to five points with a draw, with Wales at best moving up to third on two points.
With Iran and USA – second and third respectively – facing each other, only one side can finish above England.
England, meanwhile, can lose to Wales and still progress. In fact, even with a 3-0 defeat to Wales they would still go through.
To guarantee first place in the group, however, they will need to beat Wales.
After their victory over Wales, Carlos Quieroz’s side could seal qualification with a victory over the United States…